Loren Brichter, creator of Tweetie for Mac OS X and the iPhone on Adobe AIR in an interview with Macworld:

And AIR apps are like modern day Java applets... sure, they run on every platform. But they also suck on every platform.

I have been dying for a native, elegant, multi account Twitter client for Mac OS X for months. It seems that the Adobe AIR runtime was invented for making Twitter clients. Tweetie is the best, and I couldn't be happier that Loren Brichter feels the same way I do about Java and Adobe runtimes.